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Suboptimum Vaccination Coverage Raises Serious Doubts About Reaching Target Of Eliminating Measles In Europe By 2010A study of measles data from 32 European countries* has revealed more than 12,000 cases of the disease in a two-year period (2006-07), mostly in unvaccinated or incompletely vaccinated children. The cases, which came mainly from Romania, Germany, UK, Switzerland, and Italy, raise serious doubts that the goal of elimination of measles in Europe by 2010 can take place with suboptimum vaccination rates.medicalnewstoday.comClinical Trials Of Experimental Breast Cancer Vaccine Expected To Begin In SpringScientists from the University of Arkansas for Medical Sciences this spring expect to begin the first of two phases of clinical trials for a vaccine designed to prevent the recurrence of breast cancer, the AP/FoxNews.com reports.medicalnewstoday.comNews From The Journal Of Neuroscience, 6-Jan-20091. Exocytosis Can Form Stable Membrane Deposits in Neurons Joris de Wit, Ruud F. Toonen, and Matthijs Verhage. Neurons secrete neuropeptides, neurotrophic factors, guidance molecules, and proteases via secretory dense-core vesicles. Although secretion of such molecules has been extensively studied in neuroendocrine cells, relatively little is known about release of these molecules by neurons. To remedy this, de Wit et al.medicalnewstoday.comStudy Demonstrates That AHCC(R) Enhances Immune System By Increasing The Production Of Key Dendritic CellsA recently published study in Nutrition and Cancer (60(5), 643-651) by researchers at Kansai Medical University in Osaka, Japan has shown that AHCC (Active Hexose Correlated Compound) enhances immune function by increasing the number of dendritic cells (DCs). DCs are a key part of the immune system responsible for presenting foreign substances to other immune system cells.medicalnewstoday.comMeasles Eradication By 2010 Unlikely Say ExpertsThe global plan to eradicate measles by 2010 is unlikely to come about say epidemiology experts because of high rates of infection in some parts of Europe where many children go unvaccinated. The research was the work of Dr Mark Muscat, of the Department of Epidemiology at Statens Serum Institut in Copenhagen, Denmark, and colleagues, and is published early online on 7 January in The Lancet.medicalnewstoday.comOffspring Benefit From Disease Clues During PregnancyWhen there is a threat of disease during pregnancy, mothers produce less aggressive sons with more efficient immune systems, researchers at The University of Nottingham have discovered. The study provides the first evidence for a transgenerational effect on immune response based on environmental cues - with maternal perception of disease risk in the immediate environment potentially determining offspring disease resistance and social dominance.medicalnewstoday.comDiscovery Of Uncultured Bacteria In Amniotic Fluids Of Women Who Experience Preterm BirthsResearchers from Case Western Reserve University and Yale University have made a significant advancement in understanding the cause behind why some pregnant women suffer from inflammations in the inner womb without any signs of an infection.medicalnewstoday.comOur Antibodies Take 'Evolutionary Leaps' To Fight MicrobesWith cold and flu season in full swing, the fact that viruses and bacteria rapidly evolve is apparent with every sneeze, sniffle, and cough. A new report in the January 2009 issue of The FASEB Journal (http://www.fasebj.org), explains for the first time how humans keep up with microbes by rearranging the genes that make antibodies to foreign invaders.medicalnewstoday.comNews From The Annals Of Internal Medicine Jan. 6, 20091. Outbreaks of Viral Hepatitis Linked to Lapses in Infection Control Practices in Health Care Settings While transmission of Hepatitis B (HBV) and Hepatitis C (HCV) virus in health care settings is considered rare, recent reports of outbreaks indicate a growing problem. Over the past decade, there have been 33 outbreaks in nonhospital health care settings in the United States.medicalnewstoday.comInflammatory Factors And Diabetic Macular Edema Highlighted In Ophthalmology Jan. 2009With a new study from the Centers for Disease Control and Prevention predicting that diabetic retinopathy will triple from 5.5 million in 2005 to 16 million in 2050, improved treatments are urgently needed for this leading cause of blindness in working-age people. The CDC study is the latest indicator of a world-wide diabetes epidemic that is motivating ophthalmic research around the globe.medicalnewstoday.comPneumococcal Vaccine Does Not Appear To Protect Against PneumoniaCommonly used pneumococcal polysaccharide vaccines do not appear to be effective for preventing pneumonia, found a study by a team of researchers from Switzerland and the United Kingdom. In many industrialized countries, polysaccharide pneumococcal vaccines (PPVs) are currently recommended to help prevent pneumococcal disease in people aged 65 and over and for younger people with increased risk due to conditions like HIV.medicalnewstoday.comPain Caused By Physical Insult Sensed By Nerve Cells In The Brain And Spinal CordThe most common way of managing the pain that accompanies inflammation is to use drugs such as aspirin and ibuprofen. These work by selectively blocking the protein COX2, which functions to produce soluble molecules known as prostaglandins.medicalnewstoday.comPhase III Trial Begins For GAMMAGARD LIQUID Plus RHuPH20 In Primary Immunodeficiency PatientsBaxter International Inc. and Halozyme Therapeutics, Inc. (Nasdaq: HALO) announced the start of a Phase III clinical trial of Baxter's GAMMAGARD LIQUID [Immune Globulin Intravenous] 10% (IGIV), marketed as KIOVIG in the European Union, with Halozyme's recombinant human hyaluronidase enzyme (rHuPH20, Enhanze(TM) Technology) for the treatment of primary immunodeficiency (PID).medicalnewstoday.comNew Congenital Neutropenia Syndrome And Causative Gene Mutation Identified By ScientistsA team of scientists has discovered a new syndrome associated with severe congenital neutropenia (SCN), a rare disorder in which children lack sufficient infection-fighting white cells, and identified the genetic cause of the syndrome: mutations in the gene Glucose-6-phosphatase, catalytic subunit 3 (G6PC3). The findings, which are published in the Jan.medicalnewstoday.comAntioxidants Offer Pain Relief In Patients With Chronic PancreatitisAntioxidant supplementation was found to be effective in relieving pain and reducing levels of oxidative stress in patients with chronic pancreatitis (CP), reports a new study in Gastroenterology. CP is a progressive inflammatory disease of the pancreas in which patients experience abdominal pain (in early stage) and diabetes and maldigestion (in late stage).medicalnewstoday.comESTEVE And IRSICAIXA Sign Partnership Agreement For The Development Of A Vaccine Aimed To Eradicate AIDS In The Next 10 YearsSpain leads the most important and ambitious EU research fight AIDS project Chemical/pharmaceutical ESTEVE group signs partnership agreement with IrsiCaixa AIDS Research Institute, allowing ESTEVE to join research project. Partnership has been driven by Obra Social "La Caixa" and the Generalitat de Catalunya health department.medicalnewstoday.comNovartis Strengthens Vaccine Pipeline With Agreement For Novel CMV Vaccines CandidateNovartis has strengthened its vaccines pipeline through an exclusive agreement to license AlphaVax' investigational Cytomegalovirus (CMV) vaccine program. This CMV agreement adds to Novartis' promising early stage pipeline of novel vaccines, which focuses on significant unmet needs for the prevention of fatal diseases such as meningococcal infections and other hospital and community acquired infections.medicalnewstoday.comStudy Shows Correlation In New Mexico Between Childhood Immunization Rates And Medicaid EnrollmentNew Mexico has the highest proportion of children in the nation enrolled in Medicaid. An article published in the online, open-access journal PLoS ONE highlights research showing that childhood immunization rates in the state suffered when barriers increased to children's receiving Medicaid coverage. Researchers at the University of Toronto, University of New Mexico, and New Mexico Department of Health conducted the study. Dr.medicalnewstoday.comDiamyd Medical: New Study Application To Vaccinate Against Juvenile Diabetes With Diamyd®Diamyd Medical AB (publ.) (Pink Sheets:DMYDY) (STO:DIAMB): A renowned research group at Lund University has filed an application with the Swedish Medical Products Agency to carry out a study of the diabetes vaccine Diamyd® for the prevention of type 1 diabetes in Swedish children. This is the second prevention study with the diabetes vaccine Diamyd® for which approval has been sought in a short period.medicalnewstoday.comDynavax Announces Termination Of Partnership With Merck For HEPLISAV™ Hepatitis B Vaccine - All Rights Revert To DynavaxDynavax Technologies Corporation (Nasdaq:DVAX) today announced the termination of a global license and development collaboration agreement with Merck & Co., Inc. for HEPLISAVTM, a Phase 3 hepatitis B virus (HBV) vaccine. All rights to develop and commercialize HEPLISAV revert to Dynavax.medicalnewstoday.comCancer Drug Effectively Treats Transplant RejectionsUniversity of Cincinnati (UC) researchers have discovered a new therapy for transplant patients, targeting the antibody-producing plasma cells that can cause organ rejection. Results of the study are published in the Dec. 27, 2008, edition of the journal Transplantation.medicalnewstoday.comUT Public Health Researchers Find Link To Severe Staph InfectionsResearchers at The University of Texas School of Public Health recently described studies that support the link between the severity of community-acquired antibiotic-resistant Staphylococcus aureus (CA MRSA) infections and the Panton Valentine leukocidin (PVL). The Panton Valentine leukocidin is made up of two components - LukF-PV and LukS-PV - and is typically produced by community-acquired methicillin-resistant S. aureus (CA MRSA).medicalnewstoday.comImmunoCellular Therapeutics' Cancer Vaccine Demonstrates Immune Response Against Brain Cancer In Clinical TrialImmunoCellular Therapeutics, Ltd. (OTCBB:IMUC) (IMUC), a biotechnology company, presented preliminary, promising clinical data from a Phase I trial, evaluating ICT-107, the company's dendritic cell-based cancer vaccine product candidate for the treatment of glioblastoma. ICT-107 was well tolerated, and no significant adverse events were reported. These data were reported at the Society for Neuro-Oncology 13th Annual Scientific Meeting in Las Vegas, Nevada.medicalnewstoday.comScientists Reveal Structure Of New Botulism Nerve Toxin SubtypeScientists at the U.S. Department of Energy's (DOE) Brookhaven National Laboratory have determined the atomic-level structure of a third subtype of botulinum neurotoxin - a deadly toxin produced by certain bacteria that causes the disease botulism, and is also used in cosmetic and therapeutic applications such as reducing wrinkles and calming a hyperactive bladder.medicalnewstoday.comPotential Autoimmunity-Inducing Cells Found In Healthy AdultsIt's not just patients with autoimmune diseases like lupus and rheumatoid arthritis (RA) that have self-attacking immune cells - healthy people have them too, according to a new report in the Journal of Experimental Medicine. In healthy adults, however, these cells are maintained in an 'off' state, perhaps explaining their innocuous nature.medicalnewstoday.com
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